VivoAnimals Essential Detoxification products use human grade ingredients—organic, non-GMO or wild-crafted wherever possible. These proprietary products are veterinarian formulated using orthomolecular medicine principles; a field of medicine which proposes that optimum health can be established through the use of small quantities of a broad spectrum of complementary nutrients.
Syzygium anisatum (formerly Backhousia anisata, Anetholea anisata)

Also known as: anise myrtle, aniseed myrtle, ringwood
The anise myrtle tree is indigenous to the subtropical rainforest of the Bellinger and Nambucca valleys in New South Wales. Its numbers were dramatically reduced since the 1800s as settlers cleared the rainforests of the coastal regions for dairy farming and timber. Only recently have local growers begun replanting, fortified by the burgeoning national movement to bring back native Australian "bush foods" as viable alternative crops.
Anise myrtle is distilled to produce the essential oil, or it is harvested and dried as whole leaf or ground. The leaf is one of the highest known sources of anethole, an aromatic unsaturated ether with the full chemical name of trans-1-methoxy-4-(prop-1-enyl)benzene.

Used for thousands of years in folk medicine, anethole is well-regarded for its therapeutic properties, including applications as an antiseptic, carminative, sedative and expectorant. Plants containing anethole have traditionally been used to assist with weight loss, lactation and stomach complaints. Recently, the pure compound anethole has shown promise in treating certain types of cancer, and research by Charles Sturt University has revealed the essential oil of Syzygium anisatum to be a valuable antimicrobial agent, effective against several bacteria as well as the pathogenic yeast Candida albicans.
Tasmannia lanceolata (Drimys lanceolata, Drimys aromatica, Tasmannia aromatica, Winterania lanceolata)

Also known as: Mountain pepperbush, Tasmanian pepper, alpine pepper
The natural range of this evergreen shrub stretches from the island of Tasmania up along the east coast of Australia from Victoria to Queensland, where it can be found in moist mountain forests as well as alpine zones to 1500m. The majority of mountain pepper leaves and berries are harvested in the wild, although cultivation is increasing in Tasmania, Victoria and South Australia.
Traditionally considered “bush medicine” by Australian aborigines, the mountain pepper plant has been used as an anti-arthritic as well as a digestive aid. Almost 50 years ago, scientists researching this plant found a dominant component of the leaves and berries to be polygodial, a bicyclic sesquiterpene dialdehyde(1R-(1α,4aβ.8aα)]-1,4,4a,5,6,7,8,8a-Octahydro-5,5,8a-trimethyl-1,2-Naphthalenedicarboxaldehyde). This substance is now considered by many to be nature’s most powerful antioxidant, with stronger radical scavenging activity than blueberries. It is currently being investigated as a treatment for asthma, allergies, and other inflammatory processes.

The potent antimicrobial and antifungal properties of polygodial have been well documented. In a recent study, the compound demonstrated significant activity against gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus and gram-negative bacteria including Escherichia coli and Salmonella choleraesuis. In earlier research, polygodial showed strong and rapid antifungal activity, comparable to amphotericin B, against yeast-like fungi Candida albicans, Candida krusei, Candida utilis, Cryptococcus neoformans, Saccharomyces cerevisiae and also filamentous fungi Trichophyton mentagraphytes, Trichophyton ruburum and Penicillium marneffei. The synergistic effect of polygodial when used with other antimicrobial/antifungal agents such as anethole (see Australian anise) also shows considerable promise.
Backhousia citriodora

Also known as: lemon myrtle, lemon-scented myrtle, sweet verbena myrtle, sweet verbena tree, lemon-scented verbena
The Australian myrtle tree is native to the subtropical and tropical rainforests of eastern Australia, where for hundreds of years aborigines have exploited the healing properties of this flowering plant. Early in the last century the tree was valued for the intense citrus flavor of its leaves, but the resurgence of the Australian myrtle as a new crop within the last 20 years is due primarily to its popularity as a fragrant ornamental. Most commercial cultivation now occurs in southern Queensland and along the north coast of New South Wales. Harvested leaves are dried and used in culinary applications or distilled to produce an essential oil consisting of approximately 0.1-1% citronellal and up to 98% citral, an aliphatic aldehyde of the monoterpenoid class which is responsible for most of the lemon scents and flavors in nature. This high percentage makes the Australian myrtle the richest natural source of citral.
The antimicrobial properties of Australian myrtle oil were documented by European settlers as far back as the 1920s, and a 1950s study proved B. citriodora to be among the most potent of native Australian plants tested for antibacterial activity. More current research has indicated the plant’s essential oil is particularly effective against the fungus Aspergillus but also quite successful in inhibiting the growth of a number of other microorganisms, including Candida albicans, Salmonella typhi, Clostridium perfringens, Pseudomonas aeruginosa and a hospital isolate of methicillin-resistant Staphylococcus aureus (MRSA). The antimicrobial activity of Australian myrtle leaf essential oil was found to be greater than that of citral alone and often superior to tea tree oil. Recently, Australian myrtle oil has been used to successfully treat children suffering from the viral skin condition molluscum contagiosum.

The antimicrobial, antispasmodic and sedative properties of the Australian myrtle leaf have resulted in its therapeutic use in combating such conditions as the common cold, influenza, sinusitis, bronchitis and bronchial asthma, chest congestion, upper respiratory infections, throat disorders, indigestion and other GI complaints, gastric ulcers caused by Helicobacter pylori, and herpes simplex.
Garcinia mangostana Linn

The mangosteen tree is a tropical evergreen native to Southeast Asia, perhaps originating in the Moluccas and the Sunda Islands. Today it is cultivated in several countries including the U.S.; however, its intolerance to temperatures below 40°F primarily limits its domestic production to Hawaii and Puerto Rico.
The hull, or pericarp, of the mangosteen fruit is renowned in traditional folk medicine for its anti-inflammatory, antiseptic and immune-bolstering properties. In Southeast Asia, it has been used for many years to treat a wide array of diseases and conditions including skin infections, wounds, ulcers, and diarrhea. More recently it has achieved recognition as the richest naturally-occurring source of a class of polyphenolic acids known as xanthones. Of the 200+ xanthones identified, over 40 of them have been identified in the pericarp, among them alpha-, beta- and gamma-mangostin, garcinone B and garcinone E.
Over the past 30 years, scientific evidence for the therapeutic properties of mangosteen pericarp extracts has emerged with increasing frequency. Current research suggests that these xanthones may indeed be useful in the treatment of allergies and inflammation. In vitro studies have demonstrated their ability to suppress production of pro-inflammatory cytokines and to reduce prostaglandin E2 synthesis by inhibiting the activities of COX-1 and COX-2 enzymes. Alpha- and gamma-mangostins have also been shown to antagonize the activities of histamine and serotonin by acting as receptor blockers.
The powerful antioxidant activity of xanthones has been well documented. Recent investigations have shown pericarp extracts to be superior to other botanical derivatives tested in terms of their ability to scavenge free radicals and reduce ROS (reactive oxygen species) production, with researchers suggesting these unique compounds may also confer neuroprotective properties. Mangostin specifically has been shown to prevent oxidative damage of low-density lipoprotein by functioning as a free-radical scavenger. As oxidation of LDL is thought to play a role in atherosclerosis, mangostin may offer promising developments in the treatment of this disease.
A number of scientific studies reinforce the reputation of the pericarp as a strong antimicrobial. Alpha-mangostin has exhibited strong in vitro antibacterial activity against vancomycin-resistant Enterococci (VRE) as well as both methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MRSA). A clear synergistic effect has been observed when alpha-mangostin is used in conjunction with antibiotics such as vancomycin, gentamicin, ampicillin and minocycline, further supporting its therapeutic value in combating antibiotic-resistant infections. Mangostin and other xanthones from G. mangostana have demonstrated quite potent in vitro antiplasmodial activity as well as significant inhibitory effects against Mycobacterium tuberculosis, HIV-1 protease, and the fungi Fusarium oxysporum vasinfectum, Alternaria tenuis and Dreschlera oryzae.
Perhaps most striking are the recent investigations into the anticancer activity of mangosteen pericarp extracts, which have demonstrated strong antiproliferation, antioxidation and induction of apoptosis on human breast cancer cells. Garcinone E has shown potent cytotoxic effects on hepatocellular, gastric, and lung cancer cell lines. Alpha-mangostin is thought to induce apoptosis in human leukemia cells by mediating the mitochondrial pathway and shows promise in suppressing tumor development in colon carcinogenesis. These encouraging results indicate that future research will continue to explore ways in which pericarp xanthones could be potentially useful for the treatment or prevention of certain types of cancer.
Human trials show that taking ProCoQ10 results in 18 times higher blood serum levels of CoQ10 than high quality CoQ10.
How: The solubility and absobability of the CoQ10 in ProCoQ10 has been greatly increased through "ester science".
Human trials show that (at just 30gm ProCoQ10/day):
Change in Blood Plasma levels of CoQ10 with single dose.
Graph below shows concentration over next 48 hours.
Blue—ProCoQ10 water soluable complex—ng.hrs/ml=5,623
Orange—high quality CoQ10—ng.hrs/ml=305

22 subjects, 0 to 48 hours
Results: 5,623 versus 305
Eighteen times CoQ10 Concentration
Full study, Enhancement of Oral Bioavailability of coenzyme Q10, published in nutritional Research 26 (2006) 503-508. Available online at ScienceDirect.com.
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